Ichthyoses: Clinical, Biochemical, Pathogenic and Diagnostic Assessment (Current Problems in Dermatology) by Peter M. Elias, Mary L. Williams, Deborah Crumrine, Matthias Schmuth

Ichthyoses: Clinical, Biochemical, Pathogenic and Diagnostic Assessment (Current Problems in Dermatology)



Download Ichthyoses: Clinical, Biochemical, Pathogenic and Diagnostic Assessment (Current Problems in Dermatology)




Ichthyoses: Clinical, Biochemical, Pathogenic and Diagnostic Assessment (Current Problems in Dermatology) Peter M. Elias, Mary L. Williams, Deborah Crumrine, Matthias Schmuth
Language: English
Page: 154
Format: pdf
ISBN: 3805593945, 9783805593953
Publisher: S Karger Pub

The various manifestations of ichthyoses are classified either by their appearance or their molecular genetics. This volume focuses on generalized, inherited disorders of cornification, which constitute an ever-enlarging group of monogenic diseases caused by a large number of genes that affect a broad array of cellular functions. The authors' overview reflects their unique perspective that the clinical phenotype in the inherited ichthyoses mirrors a 'best attempt' by a metabolically compromised epidermis to maintain a barrier sufficiently impermeable for survival in a desiccating external environment. The basis for threats to survival is illuminated, and the systemic problems, including growth failure, also reflect a compromised barrier. A new consensus classification of these disorders is provided, and the distinguishing clinical features of each disorder are described. Further, the latest molecular genetic information is succinctly reviewed with up-to-date and comprehensive references. Yet, the major emphases of this volume are on disease pathogenesis and on the identification of key ultrastructural features. This publication will prove an invaluable aid to dermatologists, pediatric dermatologists and pediatricians dealing with patients with inherited ichthyoses. In addition, clinical geneticists and dermatopathologists will find it interesting reading. MORE EBOOKS:
Download Strategic Play: School of Chess Excellence epub
Download Using Java 2 Platform: Special Edition ebook
Download Forbidden Pleasures ebook







Tags: Ichthyoses: Clinical, Biochemical, Pathogenic and Diagnostic Assessment (Current Problems in Dermatology) ebook pdf epub djvu mobi rar
Ichthyoses: Clinical, Biochemical, Pathogenic and Diagnostic Assessment (Current Problems in Dermatology) pdf epub djvu free download
Download Ichthyoses: Clinical, Biochemical, Pathogenic and Diagnostic Assessment (Current Problems in Dermatology) free ebook pdf epub
Ichthyoses: Clinical, Biochemical, Pathogenic and Diagnostic Assessment (Current Problems in Dermatology) read online free book
Ichthyoses: Clinical, Biochemical, Pathogenic and Diagnostic Assessment (Current Problems in Dermatology) cheap ebook for kindle and nook
Peter M. Elias, Mary L. Williams, Deborah Crumrine, Matthias Schmuth ebooks and audio books
Ichthyoses: Clinical, Biochemical, Pathogenic and Diagnostic Assessment (Current Problems in Dermatology) download pdf epub rar rapidshare mediafire fileserve 4shared torrent depositfiles scribd